Clinical Integration: Medicine helps medical students and junior doctors link basic medical science with clinical context and build an appreciation of how pathophysiology manifests as recognisable clues.
The book shows readers the logical connections between patient history, examination findings, investigation results, management rationale and their underlying mechanisms. Readers learn to understand the "why and how" behind the diagnosis, investigation and management of common clinical problems.
The book uses a system-based approach to cover 100 clinical cases, from aortic dissection to urinary tract infections, via dementia and pneumothorax. Every case uses a consistent format to:
highlight the key elements of the history, examination, investigation and treatment phases of medical practice
provide rapid access to important facts
explore the links between pathophysiology and clinical clues that underpin common medical conditions
Chapter 1 Cardiology
Case 1 Aortic dissection
Case 2 Aortic stenosis
Case 3 Atrial fibrillation
Case 4 Heart failure with reduced ejection fraction
Case 5 Mitral regurgitation
Case 6 Mobitz 2 second-degree heart block
Case 7 Pericarditis
Case 8 ST elevation myocardial infarction
Case 9 Stable angina
Case 10 Ventricular tachycardia
Chapter 2 Endocrinology
Case 11 Addison’s disease
Case 12 Conn’s disease
Case 13 Cushing’s syndrome
Case 14 Hyperthyroidism
Case 15 Hypothyroidism
Case 16 Osteoporosis
Case 17 Paget’s disease of bone
Case 18 Primary hyperparathyroidism
Case 19 Type 1 diabetes mellitus
Case 20 Type 2 diabetes mellitus
Chapter 3 Gastroenterology and hepatology
Case 21 Acute pancreatitis
Case 22 Cholelithiasis, choledocholithiasis and cholecystitis
Case 23 Coeliac disease
Case 24 Decompensated liver cirrhosis
Case 25 GORD and oesophagitis
Case 26 Hepatitis A, B and C
Case 27 Inflammatory bowel disease
Case 28 Non-alcoholic fatty liver disease
Case 29 Oesophageal achalasia
Case 30 Peptic ulcer disease
Chapter 4 Haematology
Case 31 Acute myeloid leukaemia
Case 32 Chronic lymphocytic leukaemia and non-Hodgkin lymphoma
Case 33 Chronic myeloid leukaemia
Case 34 Haemolytic anaemia
Case 35 Haemophilia
Case 36 Hodgkin lymphoma
Case 37 Idiopathic thrombocytopenic purpura
Case 38 Iron-deficiency anaemia
Case 39 Multiple myeloma
Case 40 Venous thromboembolism
Chapter 5 Infectious diseases
Case 41 Cellulitis
Case 42 Gastroenteritis
Case 43 HIV/AIDS
Case 44 Infective endocarditis
Case 45 Malaria
Case 46 Meningoencephalitis
Case 47 Osteomyelitis
Case 48 Pneumonia
Case 49 Septic arthritis
Case 50 Urinary tract infections
Chapter 6 Neurology
Case 51 Acute inflammatory demyelinating polyradiculoneuropathy
Case 52 Acute intracerebral haemorrhage
Case 53 Dementia
Case 54 Motor neurone disease
Case 55 Multiple sclerosis
Case 56 Muscular dystrophy
Case 57 Myasthenia gravis
Case 58 Parkinson’s disease
Case 59 Spinal cord injury
Case 60 Stroke / transient ischaemic attack
Chapter 7 Oncology
Case 61 Breast carcinoma
Case 62 Colorectal carcinoma
Case 63 Head and neck carcinoma
Case 64 Hepatocellular carcinoma
Case 65 Melanoma
Case 66 Pancreatic carcinoma
Case 67 Prostate carcinoma
Case 68 Pulmonary carcinoma
Case 69 Renal cell carcinoma
Case 70 Testicular carcinoma
Chapter 8 Renal
Case 71 Acute kidney injury
Case 72 Chronic kidney disease
Case 73 Dialysis-related hypotension
Case 74 Hyperkalaemia
Case 75 Hypokalaemia
Case 76 Hyponatraemia
Case 77 Lupus nephritis
Case 78 Nephrolithiasis
Case 79 Nephrotic syndrome
Case 80 Renal transplant rejection
Chapter 9 Respiratory
Case 81 Acute respiratory distress syndrome
Case 82 Asbestosis
Case 83 Asthma
Case 84 Chronic obstructive pulmonary disease
Case 85 Cystic fibrosis
Case 86 Idiopathic pulmonary hypertension
Case 87 Interstitial lung disease
Case 88 Lung transplantation
Case 89 Pleural effusion
Case 90 Pneumothorax
Chapter 10 Rheumatology
Case 91 ANCA-associated vasculitis
Case 92 Ankylosing spondylitis
Case 93 Giant cell arteritis
Case 94 Gout
Case 95 Non-specific low back pain
Case 96 Osteoarthritis
Case 97 Polymyositis
Case 98 Rheumatoid arthritis
Case 99 Scleroderma
Case 100 Systemic lupus erythematosus
